Laboratory of Adipose Tissue Engineering and Physiology

Team Members

Principal Investigator

Dr. Maria A. Gonzalez Porras

Maria A. Gonzalez Porras, Ph.D.

Dr. Maria Gonzalez Porras is an Assistant Professor of Biomedical Engineering at the University of Texas at San Antonio (UTSA), where she leads research on engineering adipose tissue (fat) cell function for obesity and cancer.

She was born in Medellin, Colombia where she received her B.S. in Biomedical Engineering from the School of Engineering of Antioquia, in 2011. She did a Ph.D. in Physiology and Biomedical Engineering at the Mayo Clinic in Rochester, MN, in the Cell and Regenerative Physiology Laboratory, where she engineered nanoparticles to target motor neurons for spinal cord injury treatments.

Following a 1-year post-doctoral fellowship at the Mayo Clinic, she joined Dr. Eric Brey’s Laboratory at UTSA for 4-years where she developed strategies to target fat cells using nanotechnology and studied the fat microenvironment.

Her current research integrates physiology, stem cell biology and bioengineering to develop new fat cells targeted therapeutic systems. Her research interests lie in using multidisciplinary strategies to gain a better understanding of the cellular and microenvironmental conditions fundamental to the pathogenesis and therapy of fat metabolic dysfunctions in cancer, obesity and diabetes.

Honors and Awards

  • 2024 Voelcker Foundation Early Career Pilot Award in cancer
  • 2024 Vanderbilt Vibrant Travel Award to attend The Metabolic Physiology Meeting
  • 2023 First place UNM CTSC Bioventure 2023. Patent disclosure#2022-026
  • 2023 Gordon Research Biomaterials and Tissue Engineering Travel Award
  • 2023 Mays Cancer Center Early Career Pilot Award
  • 2020-2023 (F32) NIH Ruth L. Kirschstein National Research Service Award
  • 2006-2008 Undergraduate Honor’s list – Excellent Academic Performance
  • 2011 Undergraduate Honor’s Thesis (First undergraduate Laurate Thesis awarded at the University; Thesis with the highest honor)

María A. Gonzalez Porras

Instructors & Associates

Linda Mota Bio
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Linda Mota, Ph.D.

Dr. Linda Mota earned her Bachelor of Science in Environmental Science from the University of Texas at El Paso and her Master’s in Public Health from the University of Texas Health Science Center. She completed her PhD in Environmental Toxicology at Clemson University.

Her academic career includes roles as Adjunct Faculty at Anderson University, Visiting Research Scholar at Auburn University, Research Scientist at the University of Tennessee Health Science Center, and Instructional Assistant Professor at the University of Mississippi.

Since 2022, Dr. Mota has been part of Dr. Brey’s lab in the Department of Biomedical Engineering at UTSA, collaborating closely with Dr. Gonzalez-Porras.

As a cancer survivor and minority in STEM, she is dedicated to fostering inclusive, supportive environments that promote both scientific excellence and mental well-being. Dr. Mota values collaboration, compassion, and innovation in her work.

Linda Mota

Ph.D. Students

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David Zhang

David Zhang is a PhD student at the Department of Biomedical Engineering at UTSA. He is under the supervision of Dr. Maria González Porras with whom he is conducting research in the field of nanomedicine, drug delivery, and adipose tissue metabolism.

He received his B.S. and M.S. in Biomedical Engineering at the University of Texas at San Antonio, part of the first graduating class. Before deciding to pursue a Doctoral degree, he had three years of industry work experience with Rochal Industries under the mentorship of Dr. Ann and Joe Salamone, where he was part of the R&D team and designed novel biomaterials for wound care. During which he led a team that successfully submitted a 510(k) for a novel liquid bandage and gained FDA clearance status.

During his academia experience at UTSA, he had the privilege of serving as teaching assistant for multiple biomedical engineering courses such as physiology, biomaterials, engineering analysis, cell biology lab, and biomedical engineering lab 1, 2, and 3. His research interest involves medical device development, nanomedicine, metabolism, wound care, and clinically relevant biomedical research.

David Zhang

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Federico Zertuche González

Federico Zertuche González is an international PhD student at the University of Texas at San Antonio (UTSA), having earned his Bachelor of Biomedical Engineering from ITESM with Summa Cum Laude honors, specializing in physiological, tissue, and cardiovascular engineering. He completed a research internship at Harvard Medical School’s Division of Engineering in Medicine (2021–2022), gaining expertise in bioprinting, hydrogel matrix formation, and organ-on-chip experimentation focused on cardiac, pulmonary, and muscular tissues.

Currently, Federico’s research under Dr. Gonzalez Porras at UTSA focuses on developing novel therapeutic strategies and innovative techniques for endometrial-based pathologies, particularly studying adipose stem cell infiltration and functionality in the endometrial cancer environment, with a comprehensive analysis and modulation of oncogenic dynamics.

Dedicated to advancing tissue engineering research and its medical applications, Federico pursues lifelong learning and interdisciplinary collaboration to innovate technologies that improve global healthcare and positively impact society. Outside of his professional pursuits, he enjoys cooking, reading, sketching, and hiking.

Federico Zertuche González

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Molly Chambers

My name is Molly Chambers, and I am pursuing my Master’s Degree in Biomedical Engineering here at UTSA after earning my Bachelor’s Degree in Biomedical Engineering, also from UTSA.

My current project in GP Lab is working on understanding Adipose Stem Cell function when exposed to an Endometrial Cancer environment.

When I’m not spending hours in the lab, you can find me at the Rec where I help oversee all of our Intramural and Club Sports.

Molly Chambers

Visiting Scholars & Trainees

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Yulieth Soto

My name is Yulieth. I’m from Colombia and I’m a Biomedical Engineer.

I had the privilege of joining the GP lab in 2023 and working on the cachexia project as an international visiting student while doing my bachelor’s internship.

Currently, I’ve returned to my position as researcher to further develop the same project. My objective is to determine the effect of mitophagy inhibitors in WAT metabolism during cachexia.

Yulieth Soto

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Ashley Motola

My name is Ashley Motola and I am an undergraduate Biomedical engineering major with a concentration in Biomaterials/Tissue engineering in the NIH ESTEEMED program at UTSA. I joined the GP Lab in October of 2023. My project consists of attempting to modulate autophagy in adipocytes and STEM cells using a nanoparticle drug delivery system to study the relationship between thermogenesis and brown adipocyte formation.

During my free time, I enjoy going to the gym to destress, as well as spending time with my friends and family.

Ashley Motola

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Cody Schiferl

I started working in the Gonzalez-Porras lab in spring 2022, primarily focused on the Cachexia-Mitophagy project. My project is focused on the inhibition of mitophagy inducing proteins BNIP3 and BNIP3L to slow down or halt mitochondrial death within human adipose stem cells and mature adipocytes, slowing tissue loss in Cachexia patients.

I am set to graduate from UTSA with a BS in Biomedical Engineering in May 2025 and hope to continue my education by attending graduate school after graduation.

I was born and raised in the suburbs of Chicago, Illinois, and returned there for summer internships.

Apart from school and research, I enjoy staying active, working out and playing volleyball during my free time.

Cody Schiferl

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Breanna Herrera

My name is Breanna Herrera and I am an undergraduate student at UTSA majoring in Biomedical Engineering with a concentration in Nanobiotechnology/Biomedical Imaging.

The opportunity to join Dr. GP’s lab is such an honor, not just because I’m learning everything I can about adipocytes and their function, but because I am learning it from my colleagues!

As member of this lab, I will be collaborating with David and learning about nanoparticle targeting in adipose tissue.

The majority of my free time is spent with my family and friends, as well as playing with my five dogs. Additionally, I enjoy baking whenever I can.

Breanna Herrera

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Ethen Greenberg

I am working towards earning my B.S. in biomedical engineering by May 2026.

At the start of summer 2024, I began studying the effect cancer-associated cachexia has on mitophagy receptor proteins BNIP3/L and its role in the metabolism of different adipose tissues.

After lab, you can find me climbing, playing music, and enjoying the outdoors.

Ethen Greenberg

Jasmine Vargas Bio
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Jasmine Vargas

My name is Jasmine Vargas and I am a Biomedical Engineering Undergraduate student at UTSA with my focus in Cellular/Tissue Engineering and Biomaterials.

I joined the lab in the summer of 2024 with my focus on the effects of Saturated Fatty Acids on PAI-1 Expression in 2D and 3D Adipocytes in vitro. I am very excited to be working with other students as well as working with Dr. Gonzalez Porras and Dr. Mota.

As a member of this lab, my goal is to help advance research in the GP Fat Lab and to gain professional skills. Outside of my Academics and the Lab, I enjoy spending quality time with my family, playing with my cats and dogs, crocheting different projects, watching TV and Movies, and I occasionally read.

Jasmine Vargas

Rishi Mathew Bio
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Rishi Mathew

I am Rishi Mathew, an upcoming senior in Biomedical Engineering, concentrating on Biomaterials and Cellular Engineering.

In the GPLab, I focus on the upregulation of thermogenesis using Nanoparticles via targeted silencing of specific genes for therapeutic effects.

Outside the lab, I spend most of my free time either Backpacking or Kayaking.

Rishi Mathew

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Madeline Aguilar

Francesca Burton

Alba Chocron

María Cruz

Evelyn Fernandez

Laura Paredes

Eric Brey, Ph.D.

David Gius, M.D., Ph.D.

Nameer B. Kirma, Ph.D.

Gang Huang, Ph.D.

Achraf Noureddine, Ph.D.

Jeffrey Brinker, Ph.D.